Before you can use SPA Quick Check to validate the impact of an initialization parameter change or of gathering pending optimizer statistics, you must specify default settings for SPA Quick Check.
You will specify a default SQL tuning set for SPA Quick Check to use as one of the settings, and this SQL tuning set should include SQL statements used in the database application you are trying to tune.
It is not necessary to set default values for SPA Quick Check before using SPA Quick Check to validate the impact of implementing one or more key SQL profiles.